Good comment - I have been known to mutter about 'blowing off clots' by throwing in loads of fluid myself. We don't thrombolyse in London for exactly the reason that you mention. CO2 monitoring should be done with 'proper' difficulty in breathing, but not many people do. It is after all a good way to tell your panic attack from your pulmonary embolism. We have lifepack-12s in all of our ambulances and they accept CO2 monitoring lines. I'm completely with you of LATER. Maybe if we came across a fitter who is known to have serial seizures it might be an idea to stick a line in when they are 'quiet' rather than wait for them to start fitting again. If I recall correctly didn't the idea of permissive hypotension come from research on injuries from the Falklands war?