While the point is well-taken, can I nitpick on the detail? :-) 4mg paracetamol can't be the lethal daily dose. Typically a single paracetamol tablet can contain up to 500mg and one tends to take them two at a time... It's a unit error, right? 4 grams makes more sense, especially given the dire imprecations not to take more than 8 tablets in any 24 hour period. I'm actually in the process of trying to shake off a Solpadeine habit that... kind of snuck up on me. But it's funny: while I was taking the with-paracetamol variant, I wasn't really thinking about the paracetamol at all, because paracetamol on its own had always been completely ineffective with my headaches. Suicide wasn't even close to being my intention, I just wanted something for the headaches. (Yes, I know, it becomes self-perpetuating, with analgesia-induced headaches, and then the nasty rebound headaches when you stop.) So even at my worst I never took more than the maximum dose for a 24 hour period - in fact almost never took that much; usually just(!) 2-4 tablets on most days. But my concerns about not escalating were still based around a worry about the codeine. I didn't have any idea what a truly dangerous dose of paracetamol was and assumed there would be a certain amount of headroom in the guidelines on the boxes and leaflets. Not that I broke those guidelines except for the "if symptoms persist" part. And now i worry and wonder less at how physically crap i've been feeling. Maybe it's not too bad; I am feeling better now I've stopped and, I think, got past the rebound headaches. Because I wasn't suicidal and knew I wasn't going to OD, I tended to just think of paracetamol as benign, almost irrelevant because it never touched my headaches on its own, only really coming into effect if I had a temperature as well. I'm starting to think that was a mistake. Oddly, when I took this to a doctor, she almost laughed, and said "oh we worry when people are taking more than thirty or forty a day." I said "whaaat?" but still - based on worries about the codeine. Now I'm thinking, how did they survive that amount of paracetamol over a long period of time? I think worries about Solpadeine's addictivity have been around longer than there was a with-ibuprofen variant.