Good job of trying to explain the difference in outlook. I've tried to tell people how it feels, but never get beyond incomprehension. The hard part is getting people to notice that brain chemistry can change important parts of who you are. It's true for everybody, but it's not very comforting, and if they don't want to get that, they can't get any of it. At which point comes the inevitable comment, "Yes, but I still don't see why you can't just pull yourself together." And then the inevitable answer, "Aaaaargh."