Restless legs is one of those things that can drive you absolutely crazy. There's nothing more frustrating than being absolutely exhausted but having limbs that insist on clambering about the bed, apparently of their own accord. I nearly had to stop my antidepressant, mirtazapine, because RLS is a side effect. I need my anti depressant. My GP prescribed ropinirole. It works. Two tablets at night and I'm sleeping like a baby. It does have its own side effect, sleep 'drop outs', which can be embarrassing if you're not in bed, because you just go to sleep. Without warning. Instantly. Better than the RLS, though, and if you take it when you're already in bed then falling asleep isn't a problem.